No princípio, a botica vendia produtos farmacêuticos que o fundador representava e comercializava. Mas ao perceber que poderia produzir com qualidade os produtos extraídos da flora brasileira, ainda no final do século XIX, iniciou suas atividades produtivas, atingindo a excelência em curto espaço de tempo, ganhando notoriedade, competitividade e consequentemente o crescimento do seu negócio. A preocupação em atender com qualidade e eficácia, a um mercado latente na época, na área de saúde no Rio de Janeiro, fez da Granado referência na produção de fármacos.
Associado a competência e imbuído da inquietação, o espírito empreendedor, Cochito Granado buscou na tecnologia, a capacidade de estar cada vez melhor. Dentre os importantes títulos que a botica Granado logrou, a Pharmácia Oficial da Família Imperial Brasileira, foi o mais importante, concedido por D. Pedro II. Logo a notoriedade da marca é atingida pela comunidade científica e socialmente.
Junto ao objetivo de ser referência na produção de medicamentos, o empresário de longa visão, um verdadeiro visionário, tinha outras práticas de atuação surpreendente, a sustentabilidade, como a plantação em sua propriedade serrana de aproximadamente de 300 espécies de plantas medicinais que serviam de insumos as pesquisas para produção de novos fármacos, extratos, óleos e essências naturais. A convergência de suas ações, para êxito do seu projeto, também direcionou o visionário Granado para o uso da melhor tecnologia disponível na ocasião para a confecção de materiais impressos que serviam para a propaganda e publicidade da marca, incluindo rótulos e embalagens. Granado também investiu na formação do seu irmão Bernardo para farmacêutico, que elaborou em 1903 a fórmula do best seller da marca, dando origem ao produto centenário, hoje um ícone da marca e da farmácia brasileira, o Polvilho Antisséptico Granado.
Em 1912, a empresa aumentou sua escala de produção e diversidade de produtos com um novo laboratório, considerado o melhor e mais avançado da América do Sul. Observa-se então, que na
primeira fase de sua existência a empresa trabalhou com um mercado favorável, um empreendedor com foco nos produtos e na sua qualidade, diversidade, sofisticação e estilo, buscando formas eficazes de fabricação e viabilidade para chegar aos consumidores. Para ilustrar, apresentamos a linha Helios, o top da perfumaria na época, na versão atual da linha Vintage da Granado.
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